Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0046332 | molecular_function | SMAD binding |
| D | 0046332 | molecular_function | SMAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 601 |
| Chain | Residue |
| C | CYS247 |
| C | CYS250 |
| C | HIS262 |
| C | HIS264 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 602 |
| Chain | Residue |
| D | CYS247 |
| D | CYS250 |
| D | HIS262 |
| D | HIS264 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Necessary for heterotrimerization |
| Chain | Residue | Details |
| A | ARG515 | |
| B | ARG515 | |
| Chain | Residue | Details |
| A | LYS428 | |
| A | LYS507 | |
| B | LYS428 | |
| B | LYS507 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19135894 |
| Chain | Residue | Details |
| A | LYS519 | |
| B | LYS519 | |
