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1MQ8

Crystal structure of alphaL I domain in complex with ICAM-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, Cintercellular adhesion molecule-1polymer29131623.82UniProt (P05362)
Pfam (PF03921)
Pfam (PF21146)
In PDB
Homo sapiens (human)ICAM-1; CD54 antigen; Major group rhinovirus receptor
2B, DIntegrin alpha-Lpolymer17720191.22UniProt (P20701)
Pfam (PF00092)
In PDB
Homo sapiens (human)Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function associated molecule 1, alpha chain; CD11a
3E, F, G, H2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.44In PDB
GlyTouCan (G42666HT)
4A, C2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
5B, DMAGNESIUM IONnon-polymer24.32Chemie (MG)
6waterwater18.04Chemie (HOH)
Sequence modifications
B, D: 130 - 306 (UniProt: P20701)
PDBExternal DatabaseDetails
Cys 161Leu 186engineered mutation
Cys 299Phe 324engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight103629.9
BranchedNumber of molecules4
Total formula weight1697.6
Non-Polymers*Number of molecules6
Total formula weight933.4
All*Total formula weight106260.9
*Water molecules are not included.

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PDB entries from 2024-09-18

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