1M6D
Crystal structure of human cathepsin F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cathepsin F | polymer | 214 | 23657.7 | 2 | UniProt (Q9UBX1) Pfam (PF00112) | Homo sapiens (human) | CATSF |
| 2 | C, D (A, B) | 4-MORPHOLIN-4-YL-PIPERIDINE-1-CARBOXYLIC ACID [1-(3-BENZENESULFONYL-1-PROPYL-ALLYLCARBAMOYL)-2-PHENYLETHYL]-AMIDE | non-polymer | 582.8 | 2 | Chemie (MYP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 212 (UniProt: Q9UBX1)
| PDB | External Database | Details |
|---|---|---|
| Gln 96 | Asn 367 | engineered mutation |
| Gln 108 | Asn 378 | engineered mutation |
| Gln 167 | Asn 440 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47315.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1165.5 | |
| All* | Total formula weight | 48480.8 |
