1M5V
Transition State Stabilization by a Catalytic RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | RNA INHIBITOR SUBSTRATE | polymer | 12 | 3872.3 | 2 | |||
| 2 | B, E (M, P) | RNA INHIBITOR SUBSTRATE | polymer | 9 | 2744.7 | 2 | |||
| 3 | C, F (B, E) | RNA HAIRPIN RIBOZYME | polymer | 92 | 29809.8 | 2 | |||
| 4 | G, H (C, F) | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | polymer | 100 | 11498.5 | 2 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (human) | U1 snRNP A protein; U1 snRNP-specific protein A |
| 5 | AA, BA, CA, DA, EA... (E, B, C, D, P) | CALCIUM ION | non-polymer | 40.1 | 34 | Chemie (CA) | |||
| 6 | QA, RA (C, F) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 7 | SA, TA, UA, VA, WA... (M, B, D, P, E...) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
C, F: 1 - 100 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 31 | Tyr 31 | engineered mutation |
| Arg 36 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 95850.5 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 1599.0 | |
| All* | Total formula weight | 97449.5 |
