1M5O

Transition State Stabilization by a Catalytic RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	RNA SUBSTRATE	polymer	21	6681.9	2
2	B, E	RNA HAIRPIN RIBOZYME	polymer	92	29809.8	2
3	C, F	U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A	polymer	100	11498.5	2	UniProt (P09012) Pfam (PF00076) In PDB	Homo sapiens (human)	U1 snRNP A protein; U1 snRNP-specific protein A
4	E, A, B, C, F...	CALCIUM ION	non-polymer		40.1	37	Chemie (CA)
5		water	water		18.0	198	Chemie (HOH)

Sequence modifications

C, F: 1 - 100 (UniProt: P09012)

PDB	External Database	Details
His 31	Tyr 31	engineered mutation
Arg 36	Gln 36	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95980.3
Non-Polymers*	Number of molecules	37
	Total formula weight	1482.9
All*	Total formula weight	97463.2

*Water molecules are not included.