1LQB
Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Elongin B | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | transcription elongation factor B, polypeptide 2 |
| 2 | B (B) | Elongin C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | transcription elongation factor B (sIII), polypeptide 1 |
| 3 | C (C) | von hippel-lindau disease tumor supressor | polymer | 162 | 18702.3 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | PVHL, G7 protein |
| 4 | D (D) | Hypoxia-inducible factor 1 ALPHA | polymer | 34 | 3979.3 | 1 | UniProt (Q16665) Pfam (PF11413) | HIF-1 ALPHA | |
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
D: 549 - 582 (UniProt: Q16665)
| PDB | External Database | Details |
|---|---|---|
| Hyp 564 | Pro 564 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 46672.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 46768.9 |
