1LM8
Structure of a HIF-1a-pVHL-ElonginB-ElonginC Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | ELONGIN B | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | |
| 2 | B (C) | ELONGIN C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | |
| 3 | C (V) | Von Hippel-Lindau disease tumor suppressor | polymer | 160 | 18558.2 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | VHL |
| 4 | D (H) | Hypoxia-inducible factor 1 alpha | polymer | 20 | 2427.7 | 1 | UniProt (Q16665) Pfam (PF11413) | HIF-1 alpha, ARNT interacting protein, MOP1 | |
| 5 | E, F, G, H (B, C, V, H) | water | water | 18.0 | 523 | Chemie (HOH) |
Sequence modifications
H: 556 - 575 (UniProt: Q16665)
| PDB | External Database | Details |
|---|---|---|
| Hyp 564 | Pro 564 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44977.1 | |
| All* | Total formula weight | 44977.1 |
