1L9U

THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, J, K	RNA POLYMERASE, ALPHA SUBUNIT	polymer	314	34830.9	4	UniProt (Q9KWU8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Thermus aquaticus
2	C, L	RNA POLYMERASE, BETA SUBUNIT	polymer	1118	124800.9	2	UniProt (Q9KWU7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB	Thermus aquaticus
3	D, M	RNA POLYMERASE, BETA-PRIME SUBUNIT	polymer	1524	171187.5	2	UniProt (Q9KWU6) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Thermus aquaticus
4	E, N	RNA POLYMERASE, OMEGA SUBUNIT	polymer	99	11642.4	2	UniProt (Q9EVV4) Pfam (PF01192) In PDB	Thermus aquaticus
5	H, Q	SIGMA FACTOR SIGA	polymer	332	38186.7	2	UniProt (Q9EZJ8) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) In PDB	Thermus aquaticus
6	D, M	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	D, M	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

C, L: 1 - 1119 (UniProt: Q9KWU7)

PDB	External Database	Details
-	Glu 622	deletion

H, Q: 92 - 438 (UniProt: Q9EZJ8)

PDB	External Database	Details
-	Ile 156	deletion
-	Gln 157	deletion
-	Lys 158	deletion
-	Ile 159	deletion
-	Pro 160	deletion
-	Gly 161	deletion
-	Leu 162	deletion
-	Lys 163	deletion
-	Glu 164	deletion
-	Lys 165	deletion
-	Pro 166	deletion
-	Asp 167	deletion
-	Pro 168	deletion
-	Lys 169	deletion
-	Thr 170	deletion

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	830958.7
Non-Polymers*	Number of molecules	6
	Total formula weight	310.2
All*	Total formula weight	831268.9

*Water molecules are not included.