1KZK
JE-2147-HIV Protease Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10801.8 | 2 | UniProt (P03369) Pfam (PF00077) | Human immunodeficiency virus | Retropepsin |
| 2 | C (A) | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide | non-polymer | 575.7 | 1 | BIRD (PRD_000566) Chemie (JE2) | |||
| 3 | D, E, J, K, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 4 | F, G, H, I, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21603.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1063.3 | |
| All* | Total formula weight | 22666.8 |
