Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE JE2 A 701 |
| Chain | Residue |
| A | LEU23 |
| A | ILE50 |
| A | PRO81 |
| A | HOH1037 |
| A | HOH1040 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP30 |
| B | ILE47 |
| B | GLY48 |
| A | ASP25 |
| B | GLY49 |
| B | ILE50 |
| B | VAL82 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 901 |
| Chain | Residue |
| A | HOH932 |
| B | HOH938 |
| B | HOH991 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 902 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 903 |
| Chain | Residue |
| A | PRO39 |
| A | GLY40 |
| B | MET36 |
| B | ASN37 |
| B | HOH954 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 904 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 905 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH967 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 801 |
| Chain | Residue |
| A | GLU21 |
| A | GLU34 |
| A | VAL82 |
| A | ASN83 |
| A | HOH999 |
| B | LYS7 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 802 |
| Chain | Residue |
| A | GLN2 |
| A | HOH910 |
| B | GLU35 |
| B | LYS55 |
| B | ARG57 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 803 |
| Chain | Residue |
| A | THR12 |
| A | LYS41 |
| A | TRP42 |
| A | HOH924 |
| A | HOH983 |
| A | HOH1007 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 804 |
| Chain | Residue |
| A | ARG14 |
| A | GLY16 |
| A | GLY17 |
| A | HOH977 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 805 |
| Chain | Residue |
| A | ASN98 |
| A | PHE99 |
| A | HOH909 |
| A | HOH911 |
| B | PRO79 |
| B | GLY94 |
| B | THR96 |
| B | HOH942 |
| B | HOH943 |
| B | HOH976 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY78 | |
| B | GLY78 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY78 | |
| B | GLY78 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
