Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE JE2 A 701 |
Chain | Residue |
A | LEU23 |
A | ILE50 |
A | PRO81 |
A | HOH1037 |
A | HOH1040 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP30 |
B | ILE47 |
B | GLY48 |
A | ASP25 |
B | GLY49 |
B | ILE50 |
B | VAL82 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | ILE47 |
A | GLY48 |
A | GLY49 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 901 |
Chain | Residue |
A | HOH932 |
B | HOH938 |
B | HOH991 |
site_id | AC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL A 902 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL B 903 |
Chain | Residue |
A | PRO39 |
A | GLY40 |
B | MET36 |
B | ASN37 |
B | HOH954 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 904 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 905 |
Chain | Residue |
A | THR74 |
A | ASN88 |
A | HOH967 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 801 |
Chain | Residue |
A | GLU21 |
A | GLU34 |
A | VAL82 |
A | ASN83 |
A | HOH999 |
B | LYS7 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 802 |
Chain | Residue |
A | GLN2 |
A | HOH910 |
B | GLU35 |
B | LYS55 |
B | ARG57 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 803 |
Chain | Residue |
A | THR12 |
A | LYS41 |
A | TRP42 |
A | HOH924 |
A | HOH983 |
A | HOH1007 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 804 |
Chain | Residue |
A | ARG14 |
A | GLY16 |
A | GLY17 |
A | HOH977 |
site_id | BC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE EDO A 805 |
Chain | Residue |
A | ASN98 |
A | PHE99 |
A | HOH909 |
A | HOH911 |
B | PRO79 |
B | GLY94 |
B | THR96 |
B | HOH942 |
B | HOH943 |
B | HOH976 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
Chain | Residue | Details |
A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | SITE: Cleavage; by viral protease => ECO:0000250 |
Chain | Residue | Details |
A | GLY78 | |
B | GLY78 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
Chain | Residue | Details |
A | GLY78 | |
B | GLY78 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a30 |
Chain | Residue | Details |
A | ASP25 | |
A | THR26 | |
B | ASP25 | |
B | THR26 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a30 |
Chain | Residue | Details |
A | ASP25 | |
B | ASP25 | |