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1KJY

Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNITpolymer32537159.32UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)ADENYLATE CYCLASE-INHIBITING G ALPHA PROTEIN
2B, D
(B, D)
REGULATOR OF G-PROTEIN SIGNALING 14polymer364093.62UniProt (O08773)
Pfam (PF02188)
RGS14
3E, F, G, H, I...
(A, C, D)
CESIUM IONnon-polymer132.915Chemie (CS)
4L, V
(A, C)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
5M, N
(B, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6AA, X, Y, Z
(D, A, B, C)
waterwater18.0206Chemie (HOH)
Sequence modifications
A, C: 30 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Gly 30Ala 29SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight82505.9
Non-Polymers*Number of molecules19
Total formula weight2928.6
All*Total formula weight85434.5
*Water molecules are not included.

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PDB entries from 2025-07-02

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