1K6Y
Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Integrase | polymer | 212 | 23319.5 | 4 | UniProt (Q72498) Pfam (PF02022) Pfam (PF00665) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 | |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B, C, D | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 5 | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 212 (UniProt: Q72498)
| PDB | External Database | Details |
|---|---|---|
| Asp 131 | Trp 846 | engineered mutation |
| Asp 139 | Phe 854 | engineered mutation |
| Lys 185 | Phe 900 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93278.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 797.9 | |
| All* | Total formula weight | 94075.9 |
