1K6Y

Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0008270	molecular_function	zinc ion binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
C	0008270	molecular_function	zinc ion binding
C	0015074	biological_process	DNA integration
D	0003676	molecular_function	nucleic acid binding
D	0008270	molecular_function	zinc ion binding
D	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	HIS12
A	HIS16
A	CYS40
A	CYS43

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 402

Chain	Residue
B	HIS12
B	HIS16
B	CYS40
B	CYS43

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 403

Chain	Residue
C	HIS16
C	CYS40
C	CYS43
C	HIS12

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 404

Chain	Residue
D	HIS12
D	HIS16
D	CYS40
D	CYS43

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K A 451

Chain	Residue
A	VAL37
A	ALA38
A	CYS40
A	CYS43

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K B 452

Chain	Residue
B	VAL37
B	ALA38
B	CYS40
B	CYS43

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 453

Chain	Residue
C	VAL37
C	ALA38
C	CYS40
C	CYS43

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K D 454

Chain	Residue
D	VAL37
D	ALA38
D	CYS40
D	CYS43

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 501

Chain	Residue
A	CYS65
A	THR66
A	HIS67
A	ASN155
A	LYS159
D	HIS171

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 B 502

Chain	Residue
B	THR66
B	HIS67
B	SER119

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 C 503

Chain	Residue
C	THR66
C	HIS67
C	LYS159

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 D 504

Chain	Residue
D	THR66
D	HIS67
D	LYS159

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	164
Details	Zinc finger: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---