1K3B
Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | dipeptydil-peptidase I exclusion domain | polymer | 119 | 13500.2 | 1 | UniProt (P53634) Pfam (PF08773) | Homo sapiens (human) | DPPI, cathepsin C, residual propart |
| 2 | B (B) | dipeptydil-peptidase I light chain | polymer | 164 | 18491.9 | 1 | UniProt (P53634) Pfam (PF00112) | Homo sapiens (human) | DPPI, cathepsin C, beta chain |
| 3 | C (C) | dipeptydil-peptidase I heavy chain | polymer | 69 | 7583.4 | 1 | UniProt (P53634) | Homo sapiens (human) | DPPI, cathepsin C, alpha chain |
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, G, H (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | F (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | I, J, K (A, B, C) | water | water | 18.0 | 464 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 39575.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 544.9 | |
| All* | Total formula weight | 40120.3 |
