1JT7
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | acidic fibroblast growth factor | polymer | 146 | 16720.8 | 4 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | HEPARIN-BINDING GROWTH FACTOR 1, HBGF-1, AFGF |
2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A, C | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
4 | water | water | 18.0 | 459 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Phe 44 | Leu 59 | engineered mutation |
Val 73 | Leu 88 | engineered mutation |
Leu 109 | Val 124 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 66883.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 476.3 | |
All* | Total formula weight | 67359.4 |