1JT7

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	acidic fibroblast growth factor	polymer	146	16720.8	4	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	HEPARIN-BINDING GROWTH FACTOR 1, HBGF-1, AFGF
2	E, G, H, J (A, B, C, D)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	F, I (A, C)	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
4	K, L, M, N (A, B, C, D)	water	water		18.0	459	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Phe 44	Leu 59	engineered mutation
Val 73	Leu 88	engineered mutation
Leu 109	Val 124	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66883.1
Non-Polymers*	Number of molecules	6
	Total formula weight	476.3
All*	Total formula weight	67359.4

*Water molecules are not included.