1JL0
Structure of a Human S-Adenosylmethionine Decarboxylase Self-processing Ester Intermediate and Mechanism of Putrescine Stimulation of Processing as Revealed by the H243A Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME | polymer | 334 | 38298.4 | 2 | UniProt (P17707) Pfam (PF01536) | Homo sapiens (human) | ADOMETDC |
| 2 | C, E (A, B) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 2 | Chemie (PUT) | |||
| 3 | D, F (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 806 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 334 (UniProt: P17707)
| PDB | External Database | Details |
|---|---|---|
| Ala 243 | His 243 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76596.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 420.6 | |
| All* | Total formula weight | 77017.5 |
