1JK8
Crystal structure of a human insulin peptide-HLA-DQ8 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class II HLA-DQ8 | polymer | 181 | 20690.1 | 1 | UniProt (Q5Y7H0) Pfam (PF00993) Pfam (PF07654) UniProt (by SIFTS) (P01909) | Homo sapiens (human) | MHC class II antigen,MHC class II protein,Major histocompatibility complex,class II,DQ alpha 1 |
| 2 | B (B) | MHC class II HLA-DQ8 | polymer | 190 | 22333.1 | 1 | UniProt (O19714) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01920) | Homo sapiens (human) | |
| 3 | C (C) | insulin B peptide | polymer | 14 | 1479.7 | 1 | UniProt (by SIFTS) (P01308) | Homo sapiens | |
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 2 - 181 (UniProt: Q5Y7H0)
| PDB | External Database | Details |
|---|---|---|
| Ala 157 | Asp 183 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44502.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 44724.1 |
