1JCS
CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT | polymer | 377 | 44098.1 | 1 | UniProt (Q04631) Pfam (PF01239) In PDB | Rattus norvegicus (Norway rat) | CAAX FARNESYLTRANSFERASE ALPHA SUBUNIT; RAS PROTEINS PRENYLTRANSFERASE ALPHA; FTASE-ALPHA; PRENYL-PROTEIN TRANSFERASE RAM2 HOMOLOG |
| 2 | B | PROTEIN FARNESYLTRANSFERASE, BETA SUBUNIT | polymer | 437 | 48722.3 | 1 | UniProt (Q02293) Pfam (PF00432) In PDB | Rattus norvegicus (Norway rat) | CAAX FARNESYLTRANSFERASE BETA SUBUNIT; RAS PROTEINS PRENYLTRANSFERASE BETA; FTASE-BETA; PRENYL-PROTEIN TRANSFERASE DPR1/RAM1 SUBUNIT |
| 3 | C | SYNTHETIC HEXAPEPTIDE TKCVFM | polymer | 6 | 728.9 | 1 | |||
| 4 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | B | [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID | non-polymer | 359.4 | 1 | Chemie (FII) | |||
| 6 | B | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 7 | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93549.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 544.9 | |
| All* | Total formula weight | 94094.3 |
