1J5O
CRYSTAL STRUCTURE OF MET184ILE MUTANT OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DOUBLE STRANDED DNA TEMPLATE-PRIMER
Replaces: 1C9REntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | 5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3' | polymer | 19 | 5864.8 | 1 | |||
| 2 | B (P) | 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3' | polymer | 18 | 5484.5 | 1 | |||
| 3 | C (A) | Reverse transcriptase | polymer | 558 | 64256.6 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | HIV-1 RT |
| 4 | D (B) | Reverse transcriptase | polymer | 430 | 50263.7 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | HIV-1 RT |
| 5 | E (L) | ANTIBODY (LIGHT CHAIN) | polymer | 214 | 22984.1 | 1 | Mus musculus (house mouse) | ||
| 6 | F (H) | ANTIBODY (HEAVY CHAIN) | polymer | 220 | 23457.2 | 1 | Mus musculus (house mouse) |
Sequence modifications
A: 1 - 558 (UniProt: P03366)
B: 1 - 430 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Ile 184 | Met 351 | engineered mutation |
| Ser 280 | Cys 447 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ile 184 | Met 351 | engineered mutation |
| Ser 280 | Cys 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 172310.9 | |
| All* | Total formula weight | 172310.9 |
