1IVQ
THE CRYSTALLOGRAPHIC STRUCTURE OF THE PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 WITH TWO SYNTHETIC PEPTIDIC TRANSITION STATE ANALOG INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | HIV-2 PROTEASE | polymer | 99 | 10712.3 | 2 | UniProt (P04584) Pfam (PF00077) In PDB | Human immunodeficiency virus 2 | |
| 2 | A | N~1~-{(1S,2S,4S)-1-(cyclohexylmethyl)-4-[(2,2-dimethylpropyl)carbamoyl]-2-hydroxy-5-methylhexyl}-N~2~-(quinolin-2-ylcar bonyl)-L-aspartamide | non-polymer | 609.8 | 1 | BIRD (PRD_000348) Chemie (0PX) | |||
| 3 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04584)
| PDB | External Database | Details |
|---|---|---|
| Leu 57 | Lys 142 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21424.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 609.8 | |
| All* | Total formula weight | 22034.4 |
