1IVL
THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | IGG-KAPPA M29B FV (LIGHT CHAIN) | polymer | 107 | 11664.9 | 2 | GenBank (196585) | Mus musculus (house mouse) | |
| 2 | C (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 107 (GenBank: 196585)
| PDB | External Database | Details |
|---|---|---|
| Glu 3 | Val 3 | conflict |
| Ile 21 | Leu 21 | conflict |
| Arg 32 | Asn 32 | conflict |
| Phe 34 | His 34 | conflict |
| Leu 83 | Phe 83 | conflict |
| Ala 84 | Gly 84 | conflict |
| Val 85 | Met 85 | conflict |
| Val 91 | Ser 91 | conflict |
| Ser 92 | Asn 92 | conflict |
| Glu 93 | Ser 93 | conflict |
| Phe 96 | Tyr 96 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23329.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 60.1 | |
| All* | Total formula weight | 23389.9 |
