1IQD
Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN | polymer | 211 | 22920.4 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN | polymer | 215 | 22738.4 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | HUMAN FACTOR VIII | polymer | 156 | 17744.3 | 1 | UniProt (P00451) Pfam (PF00754) | Homo sapiens (human) | COAGULATION FACTOR VII |
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 477 | Chemie (HOH) |
Sequence modifications
C: 2174 - 2329 (UniProt: P00451)
| PDB | External Database | Details |
|---|---|---|
| Cys 2296 | Ser 2315 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63403.1 | |
| All* | Total formula weight | 63403.1 |
