1IKV
K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | POL POLYPROTEIN | polymer | 560 | 64501.0 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | reverse transcriptase |
| 2 | B (B) | POL POLYPROTEIN | polymer | 427 | 49912.3 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | reverse transcriptase |
| 3 | C (A) | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE | non-polymer | 315.7 | 1 | Chemie (EFZ) |
Sequence modifications
A: 1 - 560 (UniProt: P03366)
B: 1001 - 1427 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 270 | engineered mutation |
| Gln 478 | Glu 645 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 1103 | Lys 270 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114413.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 315.7 | |
| All* | Total formula weight | 114729.0 |
