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1I7I

CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 242

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMApolymer29233209.42UniProt (P37231)
Pfam (PF00104)
In PDB
Homo sapiens (human)PPAR-GAMMA
2A, B(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACIDnon-polymer408.52Chemie (AZ2)
3waterwater18.062Chemie (HOH)
Sequence modifications
A, B: 197 - 477 (UniProt: P37231)
PDBExternal DatabaseDetails
Gly 186-cloning artifact
Ser 187-cloning artifact
His 188-cloning artifact
Met 189-cloning artifact
Ala 190-cloning artifact
Glu 191-cloning artifact
Ile 192-cloning artifact
Ser 193-cloning artifact
Ser 194-cloning artifact
Asp 195-cloning artifact
Ile 196-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66418.8
Non-Polymers*Number of molecules2
Total formula weight816.9
All*Total formula weight67235.7
*Water molecules are not included.

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PDB entries from 2024-03-27

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