1I7I
CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 242
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA | polymer | 292 | 33209.4 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-GAMMA |
| 2 | C, D (A, B) | (2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACID | non-polymer | 408.5 | 2 | Chemie (AZ2) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A, B: 197 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 186 | - | cloning artifact |
| Ser 187 | - | cloning artifact |
| His 188 | - | cloning artifact |
| Met 189 | - | cloning artifact |
| Ala 190 | - | cloning artifact |
| Glu 191 | - | cloning artifact |
| Ile 192 | - | cloning artifact |
| Ser 193 | - | cloning artifact |
| Ser 194 | - | cloning artifact |
| Asp 195 | - | cloning artifact |
| Ile 196 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66418.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 816.9 | |
| All* | Total formula weight | 67235.7 |
