1HCQ

THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, G)	DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3')	polymer	18	5501.6	2
2	B, D (D, H)	DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3')	polymer	18	5492.6	2
3	E, F, G, H (A, B, E, F)	PROTEIN (ESTROGEN RECEPTOR)	polymer	84	9711.3	4	UniProt (P03372) Pfam (PF00105)	Homo sapiens (human)
4	I, J, K, L, M... (A, B, E, F)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
5	Q, R, S, T, U... (C, D, G, H, A...)	water	water		18.0	158	Chemie (HOH)

Sequence modifications

A, B, E, F: 2 - 84 (UniProt: P03372)

PDB	External Database	Details
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	60833.3
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	61356.6

*Water molecules are not included.