1H07

CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
ACELL DIVISION PROTEIN KINASE 2polymer29934002.51
UniProt (P24941)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)@PDBjP33 PROTEIN KINASE
((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2R)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILEnon-polymer511.41
((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2S)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILEnon-polymer511.41
waterwater18.0200

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight34002.5
Non-Polymers*Number of molecules2
Total molecular weight1022.8
All*Total molecular weight35025.4
*Water molecules are not included.