1H07

CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (1.85 Å)

Cell axes53.32371.54372.550
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits32.35 - 1.85
the highest resolution shell value1.960 - 1.850
R-work0.21000
the highest resolution shell value0.221
R-free0.23500
the highest resolution shell value0.242
RMSD bond length0.006
RMSD bond angle1.200 (22.400*)

Data Collection Statistics

Resolution limits32.35 - 1.85
the highest resolution shell value -
Number of reflections21455
Number of measurements53065*
Rmerge_l_obs0.096
the highest resolution shell value0.191
Completeness88.8 (87.7*)
Redundancy2.5
the highest resolution shell value2.1

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1unknown*7unknown*

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*
Lawrie, A.M., (1997) Nat.Struct.Biol., 4, 796.