1GQF

Crystal structure of human procaspase-7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Caspase-7	polymer	265	30283.3	2	UniProt (P55210) Pfam (PF00656)	Homo sapiens (Human)	CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3
2	C, D, E, F, G (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	H, I (A, B)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, B: 140 - 402 (UniProt: P55210)

PDB	External Database	Details
Ala 285	Cys 186	engineered mutation
Leu 402	-	expression tag
Glu 402	-	expression tag
His 402	-	expression tag
His 402	-	expression tag
His 402	-	expression tag
His 402	-	expression tag
His 402	-	expression tag
His 402	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60566.7
Non-Polymers*	Number of molecules	5
	Total formula weight	480.3
All*	Total formula weight	61047.0

*Water molecules are not included.