1GOT
HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GT-ALPHA/GI-ALPHA CHIMERA | polymer | 350 | 40685.5 | 1 | UniProt (P04695) Pfam (PF00503) | Bos taurus (cattle) | |
| 2 | B (B) | GT-BETA | polymer | 340 | 37431.0 | 1 | UniProt (P62871) Pfam (PF25391) | Bos taurus (cattle) | BETA1, TRANSDUCIN BETA SUBUNIT |
| 3 | C (G) | GT-GAMMA | polymer | 73 | 8578.8 | 1 | UniProt (P02698) Pfam (PF00631) | Bos taurus (cattle) | GAMMA1, TRANSDUCIN GAMMA SUBUNIT |
| 4 | D (G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | E, F, G (A, B, G) | water | water | 18.0 | 616 | Chemie (HOH) |
Sequence modifications
A: 2 - 350 (UniProt: P04695)
| PDB | External Database | Details |
|---|---|---|
| Mse 49 | Met 48 | modified residue |
| Mse 84 | Met 83 | modified residue |
| Mse 104 | Met 103 | modified residue |
| Mse 106 | Met 105 | modified residue |
| Mse 115 | Met 114 | modified residue |
| Mse 119 | Met 118 | modified residue |
| Mse 194 | Met 193 | modified residue |
| Ala 216 | Cys 215 | conflict |
| Cys 220 | Ile 219 | conflict |
| Val 221 | Ala 220 | conflict |
| Asp 225 | Ala 224 | conflict |
| Leu 228 | Met 227 | conflict |
| Ala 231 | Val 230 | conflict |
| Glu 234 | Asp 233 | conflict |
| Mse 236 | Val 235 | conflict |
| Mse 239 | Met 238 | conflict |
| Mse 243 | Leu 242 | conflict |
| Lys 244 | His 243 | conflict |
| Asp 247 | Asn 246 | conflict |
| Asn 252 | His 251 | conflict |
| Lys 253 | Arg 252 | conflict |
| Trp 254 | Tyr 253 | conflict |
| Thr 256 | Ala 255 | conflict |
| Asp 257 | Thr 256 | conflict |
| Ile 261 | Val 260 | conflict |
| Leu 269 | Val 268 | conflict |
| Glu 271 | Ser 270 | conflict |
| Ser 277 | Ala 276 | conflict |
| Pro 278 | His 277 | conflict |
| Thr 280 | Ser 279 | conflict |
| Tyr 283 | Phe 282 | conflict |
| Glu 285 | Asp 284 | conflict |
| Ala 287 | Asn 286 | conflict |
| Ser 289 | Pro 288 | conflict |
| Glu 294 | Asp 293 | conflict |
| Mse 308 | Met 307 | modified residue |
| Mse 319 | Met 318 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86695.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.2 | |
| All* | Total formula weight | 87138.5 |
