1GOT
HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GT-ALPHA/GI-ALPHA CHIMERA | polymer | 350 | 40685.5 | 1 | UniProt (P04695) Pfam (PF00503) | Bos taurus (cattle) | |
| 2 | B (B) | GT-BETA | polymer | 340 | 37431.0 | 1 | UniProt (P62871) Pfam (PF00400) | Bos taurus (cattle) | BETA1, TRANSDUCIN BETA SUBUNIT |
| 3 | C (G) | GT-GAMMA | polymer | 73 | 8578.8 | 1 | UniProt (P02698) Pfam (PF00631) | Bos taurus (cattle) | GAMMA1, TRANSDUCIN GAMMA SUBUNIT |
| 4 | D (G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E, F, G (A, B, G) | water | water | 18.0 | 616 | Chemie (HOH) |
Sequence modifications
A: 2 - 350 (UniProt: P04695)
| PDB | External Database | Details |
|---|---|---|
| Mse 49 | Met 48 | modified residue |
| Mse 84 | Met 83 | modified residue |
| Mse 104 | Met 103 | modified residue |
| Mse 106 | Met 105 | modified residue |
| Mse 115 | Met 114 | modified residue |
| Mse 119 | Met 118 | modified residue |
| Mse 194 | Met 193 | modified residue |
| Ala 216 | Cys 215 | conflict |
| Cys 220 | Ile 219 | conflict |
| Val 221 | Ala 220 | conflict |
| Asp 225 | Ala 224 | conflict |
| Leu 228 | Met 227 | conflict |
| Ala 231 | Val 230 | conflict |
| Glu 234 | Asp 233 | conflict |
| Mse 236 | Val 235 | conflict |
| Mse 239 | Met 238 | conflict |
| Mse 243 | Leu 242 | conflict |
| Lys 244 | His 243 | conflict |
| Asp 247 | Asn 246 | conflict |
| Asn 252 | His 251 | conflict |
| Lys 253 | Arg 252 | conflict |
| Trp 254 | Tyr 253 | conflict |
| Thr 256 | Ala 255 | conflict |
| Asp 257 | Thr 256 | conflict |
| Ile 261 | Val 260 | conflict |
| Leu 269 | Val 268 | conflict |
| Glu 271 | Ser 270 | conflict |
| Ser 277 | Ala 276 | conflict |
| Pro 278 | His 277 | conflict |
| Thr 280 | Ser 279 | conflict |
| Tyr 283 | Phe 282 | conflict |
| Glu 285 | Asp 284 | conflict |
| Ala 287 | Asn 286 | conflict |
| Ser 289 | Pro 288 | conflict |
| Glu 294 | Asp 293 | conflict |
| Mse 308 | Met 307 | modified residue |
| Mse 319 | Met 318 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86695.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.2 | |
| All* | Total formula weight | 87138.5 |
