1GKO
An Engineered Transthyretin Monomer that is Non-amyloidogenic - Unless Partially Denatured
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TRANSTHYRETIN | polymer | 127 | 13779.4 | 4 | UniProt (P02766) Pfam (PF00576) | HOMO SAPIENS (HUMAN) | TBPA, TTR, ATTR |
| 2 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met 87 | Phe 107 | engineered mutation |
| Met 110 | Leu 130 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55117.7 | |
| All* | Total formula weight | 55117.7 |
