1G9M
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G | ENVELOPE GLYCOPROTEIN GP120 | polymer | 321 | 35429.1 | 1 | UniProt (P04578) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | C | T-CELL SURFACE GLYCOPROTEIN CD4 | polymer | 185 | 20503.3 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) In PDB | Homo sapiens (human) | |
3 | L | ANTIBODY 17B, LIGHT CHAIN | polymer | 214 | 23440.0 | 1 | Homo sapiens (human) | ||
4 | H | ANTIBODY 17B, HEAVY CHAIN | polymer | 229 | 24525.6 | 1 | Homo sapiens (human) | ||
5 | A, B | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
6 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
7 | G | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
8 | water | water | 18.0 | 953 | Chemie (HOH) |
Sequence modifications
G: 83 - 127 (UniProt: P04578)
G: 195 - 297 (UniProt: P04578)
G: 330 - 492 (UniProt: P04578)
C: 1 - 185 (UniProt: P01730)
PDB | External Database | Details |
---|---|---|
Gly 79 | - | cloning artifact |
Ala 80 | - | cloning artifact |
Arg 81 | - | cloning artifact |
Ser 82 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly 128 | - | SEE REMARK 999 |
Ala 129 | - | SEE REMARK 999 |
Gly 194 | - | SEE REMARK 999 |
PDB | External Database | Details |
---|---|---|
Gly 298 | - | SEE REMARK 999 |
Ala 299 | - | SEE REMARK 999 |
Gly 329 | - | SEE REMARK 999 |
PDB | External Database | Details |
---|---|---|
Asn 184 | Ser 209 | engineered mutation |
Thr 185 | Ile 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 103897.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 734.7 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2714.6 | |
All* | Total formula weight | 107347.2 |