1G1H
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A BIS-PHOSPHORYLATED PEPTIDE (ETD(PTR)(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTEIN TYROSINE PHOSPHATASE 1B | polymer | 298 | 34688.5 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | PTP1B, PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 |
| 2 | B | BI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE | polymer | 13 | 1662.7 | 1 | |||
| 3 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ala 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36351.2 | |
| All* | Total formula weight | 36351.2 |
