1F28

CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII BOUND TO DUMP AND BW1843U89

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	THYMIDYLATE SYNTHASE	polymer	297	34403.3	4	UniProt (P13100) Pfam (PF00303)	Pneumocystis carinii
2	E, G, I, K (A, B, C, D)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	4	Chemie (UMP)
3	F, H, J, L (A, B, C, D)	S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID	non-polymer		500.5	4	Chemie (F89)
4	M, N, O, P (A, B, C, D)	water	water		18.0	500	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	137613.1
Non-Polymers*	Number of molecules	8
	Total formula weight	3234.7
All*	Total formula weight	140847.9

*Water molecules are not included.