1EY2

HUMAN HOMOGENTISATE DIOXYGENASE WITH FE(II)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HOMOGENTISATE 1,2-DIOXYGENASE	polymer	471	53648.6	1	UniProt (Q93099) Pfam (PF20510) Pfam (PF04209) In PDB	Homo sapiens (human)
2	A	FE (II) ION	non-polymer		55.8	1	Chemie (FE2)
3		water	water		18.0	232	Chemie (HOH)

Sequence modifications

A: 1 - 445 (UniProt: Q93099)

PDB	External Database	Details
Mse -25	-	expression tag
Gly -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
His -10	-	expression tag
Ile -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Lys -4	-	expression tag
His -3	-	expression tag
Mse -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Mse 1	Met 1	engineered mutation
Mse 142	Met 142	engineered mutation
Mse 172	Met 172	engineered mutation
Mse 186	Met 186	engineered mutation
Mse 283	Met 283	engineered mutation
Mse 339	Met 339	engineered mutation
Mse 343	Met 343	engineered mutation
Mse 368	Met 368	engineered mutation
Mse 396	Met 396	engineered mutation
Mse 399	Met 399	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53648.6
Non-Polymers*	Number of molecules	1
	Total formula weight	55.8
All*	Total formula weight	53704.4

*Water molecules are not included.