1EEU

M4L/Y(27D)D/Q89D/T94H mutant of LEN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN)	polymer	114	12607.9	2	UniProt (P01625) Pfam (PF07686) UniProt (by SIFTS) (P06312)	Homo sapiens (human)
2	C, D (A, B)	ISOPROPYL ALCOHOL	non-polymer		60.1	2	Chemie (IPA)
3	E, F (A, B)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, B: 1 - 108 (UniProt: P01625)

PDB	External Database	Details
Leu 4	Met 4	engineered mutation
Asp 27	Tyr 31	engineered mutation
Asp 89	Gln 95	engineered mutation
His 94	Thr 100	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25215.8
Non-Polymers*	Number of molecules	2
	Total formula weight	120.2
All*	Total formula weight	25336.0

*Water molecules are not included.