1EER
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ERYTHROPOIETIN | polymer | 166 | 18471.3 | 1 | UniProt (P01588) Pfam (PF00758) In PDB | Homo sapiens (human) | |
2 | B, C | ERYTHROPOIETIN RECEPTOR | polymer | 227 | 25186.4 | 2 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (human) | EPOBP |
3 | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01588)
B, C: 7 - 226 (UniProt: P19235)
PDB | External Database | Details |
---|---|---|
Lys 24 | Asn 51 | engineered mutation |
Lys 38 | Asn 65 | engineered mutation |
Lys 83 | Asn 110 | engineered mutation |
Asn 121 | Pro 148 | engineered mutation |
Ser 122 | Pro 149 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gln 52 | Asn 76 | engineered mutation |
Gln 164 | Asn 188 | engineered mutation |
Glu 211 | Ala 235 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 68844.2 | |
All* | Total formula weight | 68844.2 |