1EAK
Catalytic domain of proMMP-2 E404Q mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | 72 KDA TYPE IV COLLAGENASE | polymer | 421 | 47304.3 | 4 | UniProt (P08253) Pfam (PF00413) Pfam (PF00040) In PDB | HOMO SAPIENS (HUMAN) | GELATINASE A, 72 KDA GELATINASE, MATRIX METALLOPROTEINASE-2, MMP-2 |
| 2 | P, R | INHIBITOR PEPTIDE | polymer | 8 | 622.7 | 2 | SYNTHETIC CONSTRUCT | ||
| 3 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | D, A, B, C | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 6 | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 32 - 452 (UniProt: P08253)
| PDB | External Database | Details |
|---|---|---|
| Gln 404 | Glu 404 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 190462.7 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1420.3 | |
| All* | Total formula weight | 191883.0 |
