1E0O
CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | FIBROBLAST GROWTH FACTOR 1 | polymer | 140 | 15857.9 | 2 | UniProt (P05230) Pfam (PF00167) | HOMO SAPIENS (HUMAN) | ACIDIC FIBROBLAST GROWTH FACTOR |
| 2 | B, D (B, D) | FIBROBLAST GROWTH FACTOR RECEPTOR 2 | polymer | 219 | 24526.8 | 2 | UniProt (P21802) Pfam (PF07679) Pfam (PF13927) | HOMO SAPIENS (HUMAN) | |
| 3 | E (E) | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 2905.4 | 1 | In PDB GlyTouCan (G04280SJ) | |||
| 4 | F, G, H, K, O (A, B, C, D) | NICKEL (II) ION | non-polymer | 58.7 | 5 | Chemie (NI) | |||
| 5 | I, J, L, M, N (C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 80769.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 2905.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 773.8 | |
| All* | Total formula weight | 84448.5 |
