1DIA
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY249543
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE | polymer | 306 | 33338.4 | 2 | UniProt (P11586) Pfam (PF00763) Pfam (PF02882) In PDB | Homo sapiens (human) | DC301 |
| 2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | A | [[[2-AMINO-5,6,7,8-TETRAHYDRO-4-HYDROXY-PYRIDO[2,3-D]PYRIMIDIN-6-YL]-ETHYL]-PHENYL]-CARBONYL-GLUTAMIC ACID | non-polymer | 443.5 | 1 | Chemie (L24) | |||
| 4 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66676.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1930.3 | |
| All* | Total formula weight | 68607.1 |
