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1DHF

CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DIHYDROFOLATE REDUCTASEpolymer18621349.52UniProt (P00374)
Pfam (PF00186)
Homo sapiens (human)
2C, D
(A, B)
FOLIC ACIDnon-polymer441.42Chemie (FOL)
3E, F
(A, B)
waterwater18.0116Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42699.1
Non-Polymers*Number of molecules2
Total formula weight882.8
All*Total formula weight43581.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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