1DF7
DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND METHOTREXATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DIHYDROFOLATE REDUCTASE | polymer | 159 | 17661.0 | 1 | UniProt (P0A546) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) | Mycobacterium tuberculosis | DHFR |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | D (A) | METHOTREXATE | non-polymer | 454.4 | 1 | Chemie (MTX) | |||
| 5 | E, F, G, H (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | I (A) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17661.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1664.3 | |
| All* | Total formula weight | 19325.3 |
