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1D8E

Zinc-depleted FTase complexed with K-RAS4B peptide substrate and FPP analog.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AFARNESYLTRANSFERASE (ALPHA SUBUNIT)polymer37744098.11UniProt (Q04631)
Pfam (PF01239)
In PDB
Rattus norvegicus (Norway rat)FTASE
2BFARNESYLTRANSFERASE (BETA SUBUNIT)polymer43748722.31UniProt (Q02293)
Pfam (PF00432)
In PDB
Rattus norvegicus (Norway rat)FTASE
3PK-RAS4B PEPTIDE SUBSTRATEpolymer111298.71UniProt (P01116)
In PDB
4BACETATE IONnon-polymer59.01Chemie (ACT)
5B[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACIDnon-polymer359.41Chemie (FII)
6waterwater18.075Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight94119.1
Non-Polymers*Number of molecules2
Total formula weight418.4
All*Total formula weight94537.6
*Water molecules are not included.

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PDB entries from 2024-04-24

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