1CZ8
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (V, W) | Vascular endothelial growth factor A | polymer | 94 | 10999.7 | 2 | UniProt (P15692) Pfam (PF00341) | Homo sapiens (human) | VEGF-A, Vascular permeability factor, VPF |
| 2 | C, E (L, X) | LIGHT CHAIN OF NEUTRALIZING ANTIBODY | polymer | 214 | 23453.9 | 2 | Mus musculus (house mouse) | Ranibizumab Light Chain | |
| 3 | D, F (H, Y) | HEAVY CHAIN OF NEUTRALIZING ANTIBODY | polymer | 231 | 24979.9 | 2 | Mus musculus (house mouse) | Ranibizumab Heavy Chain | |
| 4 | G, H (H, Y) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J, K, L, M... (V, W, L, H, X...) | water | water | 18.0 | 419 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 118867.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 119059.2 |
