1CE8

CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	PROTEIN (CARBAMOYL-PHOSPHATE SYNTHASE)	polymer	1073	117982.7	4	UniProt (P00968) Pfam (PF02786) Pfam (PF02787) Pfam (PF02142)	Escherichia coli
2	B, D, F, H (B, D, F, H)	PROTEIN (CARBAMOYL-PHOSPHATE SYNTHASE)	polymer	382	41480.9	4	UniProt (P0A6F1) Pfam (PF00988) Pfam (PF00117) Pfam (PF07722)	Escherichia coli
3	BB, CA, DA, HA, I... (E, C, A, G)	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
4	AB, BA, CB, DB, EA... (E, B, C, H, A...)	POTASSIUM ION	non-polymer		39.1	28	Chemie (K)
5	AC, BC, FB, GB, HB... (G, E, C, A)	CHLORIDE ION	non-polymer		35.5	12	Chemie (CL)
6	CC, IB, OA, U (G, E, C, A)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
7	DC, EC, JB, KB, PA... (G, E, C, A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	8	Chemie (ADP)
8	AA, FC, IC, LB, OB... (A, G, E, C)	L-ornithine	non-polymer		132.2	8	Chemie (ORN)
9	GC, MB, SA, Y (G, E, C, A)	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
10	HC, NB, TA, Z (G, E, C, A)	TETRAETHYLAMMONIUM ION	non-polymer		130.3	4	Chemie (NET)
11	KC, LC, MC, NC, OC... (A, B, C, D, E...)	water	water		18.0	4037	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 1073 (UniProt: P00968)

PDB	External Database	Details
Asn 46	Leu 46	conflict

B, D, F, H: 2 - 380 (UniProt: P0A6F1)

PDB	External Database	Details
Gln 183	Glu 183	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	637854.3
Non-Polymers*	Number of molecules	80
	Total formula weight	8948.0
All*	Total formula weight	646802.4

*Water molecules are not included.