1C8M
REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | HUMAN RHINOVIRUS 16 COAT PROTEIN | polymer | 285 | 32501.4 | 1 | UniProt (Q82122) Pfam (PF00073) | Human rhinovirus 16 | HRV16 |
| 2 | B (2) | HUMAN RHINOVIRUS 16 COAT PROTEIN | polymer | 252 | 28096.7 | 1 | UniProt (Q82122) Pfam (PF00073) | Human rhinovirus 16 | HRV16 |
| 3 | C (3) | HUMAN RHINOVIRUS 16 COAT PROTEIN | polymer | 238 | 26314.2 | 1 | UniProt (Q82122) Pfam (PF00073) | Human rhinovirus 16 | HRV16 |
| 4 | D (4) | HUMAN RHINOVIRUS 16 COAT PROTEIN | polymer | 77 | 8268.0 | 1 | UniProt (Q82122) Pfam (PF02226) | Human rhinovirus 16 | HRV16 |
| 5 | E (1) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F (1) | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE | non-polymer | 381.3 | 1 | Chemie (W11) | |||
| 7 | G, H, I, J (1, 2, 3, 4) | water | water | 18.0 | 482 | Chemie (HOH) |
Sequence modifications
4: 1 - 77 (UniProt: Q82122)
| PDB | External Database | Details |
|---|---|---|
| Ile 24 | Leu 25 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 95180.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 446.8 | |
| All* | Total formula weight | 95626.9 |
