1C82

MECHANISM OF HYALURONAN BINDING AND DEGRADATION: STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE IN COMPLEX WITH HYALURONIC ACID DISACCHARIDE AT 1.7 A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HYALURONATE LYASE	polymer	731	83561.9	1	UniProt (Q54873) Pfam (PF08124) Pfam (PF02278) Pfam (PF02884) In PDB	Streptococcus pneumoniae
2	B, C	4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		379.3	2	In PDB GlyTouCan (G14110BE)
3	A	CACODYLATE ION	non-polymer		137.0	2	Chemie (CAC)
4	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	573	Chemie (HOH)

Sequence modifications

A: 168 - 892 (UniProt: Q54873)

PDB	External Database	Details
Val 731	Gly 731	SEE REMARK 999
His 893	-	expression tag
His 894	-	expression tag
His 895	-	expression tag
His 896	-	expression tag
His 897	-	expression tag
His 898	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	83561.9
Branched	Number of molecules	2
	Total formula weight	758.6
Non-Polymers*	Number of molecules	4
	Total formula weight	320.0
All*	Total formula weight	84640.5

*Water molecules are not included.