1C3S
CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | polymer | 375 | 42701.6 | 1 | GenBank (AAC07100) Pfam (PF00850) UniProt (by SIFTS) (O67135) | Aquifex aeolicus | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE | non-polymer | 264.3 | 1 | Chemie (SHH) | |||
| 4 | D (A) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 1 - 375 (GenBank: null)
| PDB | External Database | Details |
|---|---|---|
| Lys 35 | Leu 35 | conflict |
| Ser 75 | Cys 75 | engineered mutation |
| Ser 77 | Cys 77 | engineered mutation |
| Asn 146 | Asp 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42701.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 329.7 | |
| All* | Total formula weight | 43031.4 |
