1C3S

CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004407	molecular_function	histone deacetylase activity
A	0040029	biological_process	epigenetic regulation of gene expression
A	0045149	biological_process	acetoin metabolic process
A	0045150	biological_process	acetoin catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 951

Chain	Residue
A	ASP168
A	HIS170
A	ASP258
A	SHH952

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SHH A 952

Chain	Residue
A	HIS132
A	PHE141
A	ASP168
A	HIS170
A	PHE198
A	ASP258
A	LEU265
A	TYR297
A	ZN951
A	HOH1026
A	ASN20
A	PRO22
A	TYR91
A	TYR91
A	HIS131

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