1C3R
CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | polymer | 375 | 42701.6 | 2 | UniProt (O67135) Pfam (PF00850) In PDB | Aquifex aeolicus | |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | TRICHOSTATIN A | non-polymer | 302.4 | 2 | Chemie (TSN) | |||
| 4 | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 375 (UniProt: O67135)
| PDB | External Database | Details |
|---|---|---|
| Lys 35 | Leu 35 | conflict |
| Ser 75 | Cys 75 | engineered mutation |
| Ser 77 | Cys 77 | engineered mutation |
| Asn 146 | Asp 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85403.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 735.6 | |
| All* | Total formula weight | 86138.8 |
