1C3R
CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004407 | molecular_function | histone deacetylase activity |
| A | 0040029 | biological_process | epigenetic regulation of gene expression |
| A | 0045149 | biological_process | acetoin metabolic process |
| A | 0045150 | biological_process | acetoin catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004407 | molecular_function | histone deacetylase activity |
| B | 0040029 | biological_process | epigenetic regulation of gene expression |
| B | 0045149 | biological_process | acetoin metabolic process |
| B | 0045150 | biological_process | acetoin catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | ASP168 |
| A | HIS170 |
| A | ASP258 |
| A | TSN502 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 503 |
| Chain | Residue |
| B | ASP168 |
| B | HIS170 |
| B | ASP258 |
| B | TSN504 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TSN A 502 |
| Chain | Residue |
| A | PRO22 |
| A | HIS131 |
| A | HIS132 |
| A | PHE141 |
| A | ASP168 |
| A | HIS170 |
| A | ASP258 |
| A | LEU265 |
| A | TYR297 |
| A | ZN501 |
| A | HOH707 |
| B | GLU195 |
| B | PHE200 |
| A | ASN20 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TSN B 504 |
| Chain | Residue |
| A | GLU195 |
| A | PHE200 |
| B | ASN20 |
| B | PRO22 |
| B | HIS131 |
| B | HIS132 |
| B | PHE141 |
| B | ASP168 |
| B | HIS170 |
| B | ASP258 |
| B | LEU265 |
| B | TYR297 |
| B | ZN503 |
